Welcome to Maybridge The Maybridge portfolio offers a comprehensive range of chemistry products and services tailored to the drug discovery and biotechnology sector. For 45 years, Maybridge has been at the forefront of innovative heterocyclic building block design, fuelled by the desire to access novel molecules of pharmaceutical interest. The Maybridge portfolio is driven by a keen understanding of the needs of the medicinal chemist and is designed to expedite the drug discovery process through: REACTIVE INTERMEDIATES. The core of the Maybridge building block collection, these pharmacophorically rich intermediates are specifically designed for medicinal chemistry, allowing logical SAR development and Hit-to-Lead optimization. Many will be of particular interest as “privileged structures” while others bearing solubilizing moieties add to the pharmacokinetic profile of drug molecules. Maybridge is proud to offer a selection of new, unique reactive intermediates each month as part of its promise to constantly deliver innovative new compounds for drug discovery research. Newsletters Live stock quantities now available to view (click here for more details) Quick2LeadTM. Diverse selections of pre-weighed building blocks designed to save you time in developing those first libraries around emerging bioactive ‘hits’. The introduction of Maybridge Quick2lead compound Kits is announced. Further information can be found here. THE MAYBRIDGE SCREENING COLLECTION. A highly diverse set of over 56,000 hit-like and lead-like molecules widely acknowledged as a critical tool in screening campaigns. THE HITFINDERTM COLLECTION. 14,400 compounds selected to represent the overall diversity of the screening collection. Latest News MAYBRIDGE FRAGMENT LIBRARIES. Selections of small compounds (mw<300) taken from the Maybridge collection for use in fragment screening to further accelerate the identification of lead compounds. MAYBRIDGE CUSTOM SYNTHESIS. Provides a single point of contact for custom synthesis solutions for both the discovery and early development phases of pharmaceutical R&D - up to kilogram scale in-house, with access to multi-kilogram quantities with trusted partners. MEDICINAL CHEMISTRY SERVICES. Custom libraries for hit exploration and hit-to-lead programs, either on a FTE or fee for service basis, drawing upon our in-house medicinal chemistry expertise.
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