CHEMISTRY SERVICES FOR DRUG DISCOVERY

Benefit from our expertise in the fields of hit generation and lead optimisation - Our skilled medicinal chemistry team can efficiently design, manage and synthesise hit-to-lead medicinal chemistry programmes, as part of a collaborative or contract project.

Specific services include: hit validation & follow-up with targeted libraries SAR design and synthesis hit-to-lead medicinal chemistry programmes lead optimisation scale-up for preclinical assessment and early clinical trials

Throughout all stages of the project clear goals are identified which are in line with the clients needs to develop a potential drug in an efficient manner.

Maybridge has worked with a number of clients on a broad range of targets including proteases, kinases, hormonal receptors and GPCRs. In all cases significant innovation has been required of our chemists to ensure that the client received the best possible outcome.

The key management of this group has the industrial experience in medicinal chemistry required to help push compounds through the drug discovery process. They can help identify and achieve key goals required to keep projects on track and to help develop compounds with desirable attributes. They have a track record for putting compounds into clinical; in many cases compounds that have advanced onwards to market.